News Medical on MSN13h
Mutation in ASXL1 gene triggers chain reaction leading to blood disorders
Scientists at La Jolla Institute for Immunology (LJI) have discovered how a mutated gene kicks off a dangerous chain of ...
Researchers reveal how a gene mutation can lead to devastating blood diseases
Scientists at La Jolla Institute for Immunology (LJI) have discovered how a mutated gene kicks off a dangerous chain of ...
lupus.bmj21h
Interplay of NF-κB and PPAR-γ transcription factors in patients with juvenile systemic lupus erythematosus
Objective Juvenile SLE (jSLE) is an autoimmune disease characterised by the presence of high levels of autoantibodies, ...
Science Daily16h
Human 'domainome' reveals root cause of heritable disease
Unstable proteins are the main drivers of many different heritable diseases, according to a new study, including genetic disorders responsible for the formation of cataracts, and different types of ...
Kidney disease compromises survival of infection-fighting cells, study reveals
Fighting off infections when one has a chronic disease is a common problem, and during the COVID-19 pandemic that scenario ...
The Lancet14h
TACE plus immune checkpoint inhibitor-based systemic therapies for hepatocellular carcinoma
The advent of immunotherapy based on immune checkpoint inhibitors has improved the treatment of advanced hepatocellular ...
Unraveling the molecular mechanisms of disease-causing mutations
Most mutations which cause disease by swapping one amino acid out for another do so by making the protein less stable, ...