To overcome the inherent challenge of translation termination interference caused by stop codon reprogramming in mammalian ...

To overcome the inherent challenge of translation termination interference caused by stop codon reprogramming in mammalian ...

To overcome the inherent challenge of translation termination interference caused by stop codon reprogramming in mammalian ...

Researchers from China recently reported that it’s hard to make sense of the widespread persistence of A-to-I mRNA editing in animals Published - May 19, 2025 05:30 am IST ...

Nonsense-mediated mRNA decay (NMD) denotes the remarkable cellular surveillance system in eukaryotic cells that recognizes and eliminates mRNA encoding nonsense codons within their protein-coding ...

tRNA therapy could potentially help to counteract the effects of these mutations. The focus of current research is designing “suppressor” tRNAs that can bypass these premature stop signals and ...

Yale scientists have reprogrammed the genetic code of an organism, creating a novel genomically recoded organism (GRO) with only one stop codon, enabling the production of synthetic proteins with new ...

Attenuation of trp operon As transcription and translation can occur simultaneously in prokaryotes, while RNA polymerase is still in the process of transcription, ribosomes may start to translate the ...

Scientists have discovered that tRNAs can determine how long mRNAs exist in a cell, causing some messages to be stabilized ...

This hierarchical structure of synonymous codons is crucial for mRNA’s functional roles, particularly in therapeutics like vaccines and gene therapies. Researchers from Johnson & Johnson and the ...

This raises the question of whether dengue virus uses codons similar to that of its hosts—mosquitos and humans. This concept is called codon optimality: the effect that codon composition has on ...