BACKGROUND: Desmosomal gene variants (DGVs) have been associated with a diverse spectrum of phenotypic manifestations within ...

9. Myocardial Infarction Associated With Percutaneous Coronary Intervention (Type 4a Myocardial Infarction) e629 10. Stent/Scaffold Thrombosis Associated With Percutaneous Coronary Intervention (Type ...

Stroke prevention is central to the management of patients with AF. For many years, the use of oral anticoagulant therapy with warfarin, described as a vitamin K antagonist (VKA), has been the ...

Right ventricular pressure-volume (PV) analysis characterizes ventricular systolic and diastolic properties independent of loading conditions like volume status and afterload. While long-considered ...

Antiarrhythmic drugs (AAD) play an important role in the management of arrhythmias. Drug interactions involving AAD are common in clinical practice. As AADs have a narrow therapeutic window, both ...

Catheter ablation as first-line therapy for ventricular tachycardia (VT) at the time of implantable cardioverter defibrillator (ICD) implantation has not been adopted into clinical guidelines. Also, ...

Many features of the environment have been found to exert an important influence on cardiovascular disease (CVD) risk, progression, and severity. Changes in the environment because of migration to ...

Background— Nuclear magnetic resonance (NMR) spectroscopy measures the number and size of lipoprotein particles instead of their cholesterol or triglyceride content, but its clinical utility is ...

Delayed cerebral ischemia is a major predictor of poor outcomes in patients who suffer subarachnoid hemorrhage. Treatment options are limited and often ineffective despite many years of investigation ...

Although tortuosity of the internal carotid artery (ICA) can pose a significant challenge when performing mechanical thrombectomy, few studies have examined the impact of ICA tortuosity on mechanical ...

Accelerated biological aging is an increasingly popular way to track the acceleration of biology over time that may not be captured by calendar time. Biological aging has been linked to external and ...

Duke Congenital Heart Surgery Research and Training Laboratory, Duke University, Durham, NC (N.K.P., B.A., M.M.-M., D.M.O., J.W.T.). Department of Surgery, Duke ...