By tethering RNA polymerase with the coupling transcription factor NusG or its paralog or version, RfaH, which threads the ...

The ribosome is vital because it translates genetic instructions into proteins needed for bacterial growth. By interrupting this critical process, lariocidin effectively halts bacterial survival.

Several classes of antibiotics target the bacterial ribosome to block protein synthesis. However, ribosome modifications that disrupt antibiotic binding lead to resistance. Reporting in Cell ...

New research suggests that bacterial vaginosis can be sexually transmitted, meaning men can reinfect their female partners.

By conducting mechanistic studies on bacterial and human ribosomes, researchers can understand their similarities and differences to develop drugs and understand disease. Many antibiotics work by ...

Advanced microscopy techniques give scientists valuable clues for how to fight an enzyme that is leading to a rise in cases of antibiotic-resistant bacterial infections worldwide.

Scientists at St. Jude Children’s Research Hospital have found that human ribosomes decode mRNA slower than bacteria, with implications for drug development.

Bacterial vaginosis, which affects nearly 1 in 3 women, should be considered a sexually transmitted disease, according to a new study.

Antibiotics that inhibit protein synthesis are known to have some degree of antivirulence effects. Macrolides bind reversibly to 23S ribosomal RNA (rRNA) of the 50S subunit of bacterial ribosome ...

University of Illinois Chicago researchers developed a dual-action antibiotic that makes bacterial resistance to drugs nearly impossible.