Antibiotics that inhibit protein synthesis are known to have some degree of antivirulence effects. Macrolides bind reversibly to 23S ribosomal RNA (rRNA) of the 50S subunit of bacterial ribosome ...

The method, called ribosome profiling, delivered a surprise. On closer inspection, many of the messenger RNA molecules did not correspond to any known gene.

imageimageA screen for inducible biosensing components to drive a bacterial synthetic memory circuit is designed using barcoded libraries of sensory systems. Testing and validation in conventional ...

Insect protein blocks bacterial infection Date: June 2, 2025 Source: RMIT University Summary: Scientists in Australia have developed a smart, bacteria-repelling coating based on resilin the ultra ...

A new study, published in the Chemical Engineering Journal, reports a novel, two-step method to effectively dismantle bacterial biofilms and prevent regrowth.

Overall, this study underscores the diversity of regulatory ribosome-stalling peptides in nature, highlighting ToiL's uniqueness in sensing multiple antibiotics and offering significant insights into ...

In bacterial cells, cold shock proteins (CSPs) are expressed in response to the inhibition of translation elongation induced by environmental and intrinsic stressors. The researchers conducted a ...

Bioinformaticians have established that the genes in bacterial genomes are arranged in a meaningful order. They describe that the genes are arranged by function: If they become increasingly ...

These molecules often interact with various bacterial targets, but until now, none had been shown to block the ribosome itself. Lariocidin and its variant, lariocidin B, are produced by a strain of ...

When lariocidin binds to the bacterial ribosome, protein synthesis is prevented, and bacteria cells cannot grow or survive with synthesizing proteins. "This is a new molecule with a new mode of action ...

The ribosome is vital because it translates genetic instructions into proteins needed for bacterial growth. By interrupting this critical process, lariocidin effectively halts bacterial survival.