Viagra is so popular that its name has become synonymous with ED treatment — just like Ziploc has with plastic bags. But the active ingredient in Viagra is sildenafil. Pfizer Pharmaceuticals patented ...
Sildenafil citrate is the first phosphodiesterase type 5 (PDE-5) inhibitor approved by Food and Drug Administration (1998). PDE-5 inhibition causes an elevation in intracellular cGMP level as cGMP is ...
In both diabetic and aged ED models, there is an impaired responsiveness of the rat corpora cavernosa sinusoidal relaxation, a significant decrease in abundance of its smooth muscle and endothelium ...
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