We describe the rationale for and the synthesis of a new class of compounds utilizing a modular approach that are designed to mimic ascorbic acid and to inhibit 2-oxoglutarate-dependent hydroxylases.

ISLAMABAD: The Federal Tax Ombudsman Secretariat (FTO) on Wednesday conveyed to embassies and foreign missions that... AIRLINK 153.01 Increased By 10.18 (7.13%) BOP 10.37 Increased By 0.15 (1.47%) ...

Transpire Bio has licensed an inhaled PDE4 inhibitor from China’s Intragrand Pharma as a potential treatment for idiopathic pulmonary fibrosis (IPF), investigating a target already being pursued ...

Bayer’s Vividion Therapeutics has secured the global rights from its partner Roche to the only covalent Werner helicase (WRN) inhibitor to have made it into the clinic.. Vividion and Roche have ...

Giving atezolizumab to patients with stage 3 dMMR colon cancer after surgery and chemotherapy has reduced their risk of recurrence and death by half, a real advance.As a result of this step ...

References: Ferrer receives FDA Fast Track designation for FNP-223 in progressive supranuclear palsy (PSP). News release. Ferrer. June 17, 2025.

ROCKVILLE, Md. and SUZHOU, China, June 02, 2025 (GLOBE NEWSWIRE) -- Ascentage Pharma (NASDAQ: AAPG; HKEX: 6855), a global biopharmaceutical company dedicated to addressing unmet medical needs in ...

An SGLT2 inhibitor helped improve metabolic dysfunction-associated steatohepatitis (MASH) in people with or without type 2 diabetes, a randomized trial in China found.

N6-Methyladenosine (m6A), the most prevalent mRNA modification, undergoes dynamic regulation mediated by the demethylase fat mass and obesity-associated protein (FTO), which is aberrantly ...

Oil-insoluble silicone-based foam inhibitor additives, which are the most widely used in lubricant formulation, are not dissolved, but rather dispersed finely in the lubricating oil and very low ...

Insilico Medicine and collaborators reported promising safety and efficacy results from a Phase IIa trial of Rentosertib (known as ISM001-055), a TNIK inhibitor developed using Insilico's ...