A novel inhibitor-loaded bilayer hybrid system based on the LDH inner layer and MOF outer layer is designed on an aluminum alloy 2A12 surface to improve corrosion performance. The hybrid film system ...

EP: 2. Personalized JAK Inhibitor Selection in Myelofibrosis: Clinical Characteristics, Molecular Profiles, and Treatment Sequencing EP: 3. Myelofibrosis Management: Clinical Approaches and Treatment ...

Oil-insoluble silicone-based foam inhibitor additives, which are the most widely used in lubricant formulation, are not dissolved, but rather dispersed finely in the lubricating oil and very low ...

Purpose TLR7 and TLR8 (TLR7/8) are members of the Toll-Like Receptor family that recognize single strand RNA. Activation of TLR7/8 within immune cells elevates pro-inflammatory cytokines and type ...

The Food and Drug Administration (FDA) has received Fast Track designation for FNP-223 for the treatment of progressive supranuclear palsy (PSP). FNP-223, previously known as ASN90, is a ...

Since taking office, the Trump administration has emphasized that combating cartels and transnational criminal organizations (TCOs) is a national security priority. The administration has reinforced ...

The demethylase fat mass and obesity-related associated protein (FTO) is strongly associated with depression. Aging is a risk factor for synaptic plasticity damage in the brain and leads to ...

Mutations in MEK1/2 have been described as a resistance mechanism to BRAF/MEK inhibitor treatment. We report the discovery of a novel ATP-competitive MEK1/2 inhibitor with efficacy in wildtype (WT) ...

Objective In PAISLEY, a 48-week, phase II, randomised controlled trial that assessed deucravacitinib in patients with active SLE, all primary and secondary endpoints were met with the deucravacitinib ...

ISLAMABAD: The Federal Tax Ombudsman Secretariat (FTO) on Wednesday conveyed to embassies and foreign missions that vehicles purchased from the local market and subsequently used by Foreign ...