They put this new approach to the test finding an antibody pair for the Simple Plex Ella platform immunoassay for the cytokine IL-10. Assays for biomarkers like IL-10 must be able to precisely ...

They used a therapeutic protein—called a monoclonal antibody—that blocks the formation of this harmful type of fibroblast, and succeeded in reducing the formation of scar tissue and improving ...

Elevated IL-10 in diabetes causes capillary obstruction, linked to cognitive deficits. Blocking IL-10 receptors shows promise for improving brain function.

No writing assistance was utilized in the production of this manuscript. Monoclonal antibodies are novel therapeutic agents used with great success in the treatment of rheumatoid arthritis (RA).

In the past few years, multispecific antibodies, such as trispecific, bispecific, and tetraspecific, have become popular in antibody therapeutics. Compared to conventional monospecific antibodies ...

Antivenom (often spelled “antivenin”) is an antibody product that can disable a particular venom’s toxins. If injected quickly after a bite or sting, the antibodies in antivenom neutralize the venom, ...

"We set out to make an antibody that can recognize a single change in the 600 amino acid building blocks that make up the exposed part of the HER2 protein, which conventional wisdom says is very ...

‘Mono’ means one and 'clone' means identical copy. Monoclonal antibodies are, therefore, identical copies of one type of antibody. Antibodies bind to specific antigens on pathogens. This means ...

Immune complex formation and deposition in the kidney trigger activation of the classical pathway upon binding of C1q to an exposed antibody Fc region. C1r and C1s serine proteases are then ...

"In anti-NMDAR encephalitis, antibodies bind to those receptors and prevent them from working," he explains. As an autoimmune response, the brain becomes inflamed—hence, Brain on Fire.

Antibodies bind to specific antigens on pathogens. This means that only one type of antibody will bind to a matching antigen. For example, an antibody that can recognise an antigen on the ...