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Cell-to-cell interactions are important for the regulation of various cell activities, such as proliferation, differentiation, and apoptosis. This paper presents an approach to studying cell-to-cell ...

The promise of stem cell therapy is powerful. Scientists can draw versatile cells from the human body and deliver them to repair injuries and fight disease from the inside out. But not all stem ...

To study this, first authors Matthias Muhar, Jakob Farnung, and colleagues synthesized peptides with various chemical modifications, including glycation, carbamylation, and the amide-forming peptide ...

Quantitative elemental analysis of human leukemia K562 single cells by inductively coupled plasma mass spectrometry in combination with a microdroplet generator.

The study provides a valuable showcase of a workflow to perform large-scale characterization of drug mechanisms of action using proteomics in which on-target and off-targets of 166 compounds using ...

eLife assessment This study presents an important finding of dynamic reprogramming of global H3K4me2 during mouse oocyte-to-embryo transition. While the H3K4me2 epigenome data is convincing, the ...

In the context of cancer, lipid peroxidation contributes to tumor progression by promoting genomic instability, activating pro-inflammatory pathways, and inducing immune evasion (1 – 3). Recent years ...

Previous studies have reported that hsa-miR-145-5p and hsa-miR-203a-5p can overcome IM resistance and hsa-miR-203a-5p can alter glutathione metabolism in IM-resistant cells. The purpose of this study ...

Ultrasound single-beam acoustic tweezer system has attracted increasing attention in the field of biomechanics. Cell biomechanics play a pivotal role in leukemia cell functions. To better understand ...