Do you wake up feeling drained despite getting 9 hours of sleep? Maybe your body is lacking in vitamin B12. This essential ...

You can find B12 in four chemical compounds: methylcobalamin, hydroxocobalamin, adenosylcobalamin and cyanocobalamin. Methylcobalamin and adenosylcobalamin are in meat and dairy products.

Here, the authors show that methylcobalamin in base-off conformation coordinates to Cys180 in GSDME to prevent caspase-3/GzmB-GSDME interactions and thereby GSDME-mediated liver failure.

Disability sector leaders are pushing for fairer funding on the Border, Riverina and North East because they fear regional areas are being left behind.

Expert Rev Mol Diagn. 2012;12(7):731-754.