Assessment of Functional Status of Human Leukocyte Antigen Class I Genes in Cancer Tissues in the Context of Personalized Neoantigen Peptide Vaccine Immunotherapy Lymph node metastasis (LNM) ...
The prognostic significance of isolated tumor cells (ITCs) in lymph nodes remains uncertain, and immunohistochemistry (IHC) is not consistently used for their detection. We aimed to evaluate the ...
Major Finding: IFNγ prevents expansion of an immature, lymphatic endothelial cell state that drives lymph node metastasis. Concept: Cytotoxic immune pressure metabolically reprograms tumor‑associated ...
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