Astrocytes in the brain exhibit significant regional diversity, but the mechanisms controlling their heterogeneity remain ...

CDK4/6 inhibitors, which are already FDA approved for the treatment of other forms of cancer, show early signs of promise in the treatment of a subtype of pediatric high-grade glioma, according to ...

We also demonstrate that when glucose levels are limiting, fatty acid metabolism can support glial cell survival and the basic functional integrity of myelinated axons. Analysis of human microglia ...

It is widely accepted that cortical oligodendrocyte progenitor cells (OPCs) arise from medial ganglionic eminence (MGE), lateral/caudal ganglionic eminence (LGE/CGE), and cortical radial glial cells ...

In this manuscript the authors re-examine the developmental origin of cortical oligodendrocyte (OL) lineage cells using a combination of strategies, focussing on the question of whether the LGE ...

It's also called a transradial cardiac cath or angiography. During the procedure, a healthcare provider inserts a long thin tube (catheter) through the radial artery. The radial artery is a blood ...

Although the results from this study are encouraging, many issues remain. Considering the size of the cardiospheres, the majority of them should have been entrapped in the capillaries leading to ...

Interestingly, the impulses, also called action potentials, originate from tumor cells that are part neuron and part glia, supporting the groundbreaking idea that neurons are not the only cells ...

Notably, Coasy ablation in radial glia and astrocytic lineage triggers abnormal neuronal development and chronic neuroinflammation, offering new insights into disease mechanisms. Introduction For ...

Tau helps combat oxidative stress by aiding in the formation of lipid droplets in glial cells, which sequester toxic lipids and protect neurons. However, when Tau is mutated or absent, this protective ...

Cortical formation in the developing brain is a highly complicated process involving neuronal production (through symmetric or asymmetric cell division) interaction of radial glia with neuronal ...