In this work, we harnessed mass spectrometry for online reaction monitoring of hydroxyl radical (• OH) attack to cysteine disulfide and acquired mechanistic details that had not been achieved ...

The major task in proteomics is to understand how proteins interact with their partners. The photo-cross-linking technique enables direct probing of protein−protein interaction. Here we report the ...

ABSTRACT: Aim of Study: Ricinodendron heudelotii (Baill.) (RH) commonly called “Djansang” in Cameroon, has already been reported to possess cardioprotective effect, vasorelaxant and antioxidant ...

Cao et al. (17) found that different concentrations of H 2 O 2 affected the changes of α dynamic helix, carbonyl group, hydrogen bond, sulfhydryl group and hydrophobic stage point in G-actin, thus ...

Efficient prioritization of bioactive compounds from high throughput screening campaigns is a fundamental challenge for accelerating drug development efforts. In this study, we present the first ...