New cancer therapy strategy targets GLUT3 in regulatory T cells to supercharge anti-tumor immunity
Scientists at Pohang University of Science and Technology (POSTECH) and ShanghaiTech University have achieved a breakthrough ...
News Medical1d
Study provides new insights into the central role of goblet cells
Dr. Tonetti states, "This interplay between goblet cells and the gut microbiome is essential to sustaining both a strong ...
eLife2d
Targeting IRE1α improves insulin sensitivity and thermogenesis and suppresses metabolically active adipose tissue macrophages in obesity
Department of Physiology, Harold Hamm Diabetes Center, The University of Oklahoma Health Science Center, Oklahoma City, United States ...
The EMBO Journal4d
Hair follicle stem cells and the collapse of self-tolerance in alopecia: the interplay of barrier function, the microbiome, and immunity
In particular, the long-lived, quiescent hair follicle stem cells (HFSCs) are strikingly resistant to cytotoxic immune effectors such as T cells and natural killer (NK) cells, even in systems where ...
Increased psoriasis risk found in cancer patients treated with immune checkpoint inhibitors
Researchers from the National Defense Medical Center in Taiwan have identified an increased risk of psoriasis in patients ...
Labroots12d
Increased Immune Cell Tolerance Improves Early Pregnancy Rates
The intricate cellular details of pregnancy demonstrate the complexity of a developing fetus. In the medical community, pregnancy is considered a host-graf | Immunology ...
Deccan Chronicle14d
I-T dept notifies tolerance range for AY25 for transfer pricing cases
New Delhi: The income tax department has notified the tolerance range for variation between arm's length price and transfer pricing for international and specified domestic transactions for ...
Boosting immune cell tolerance may help prevent early pregnancy loss
Recurrent pregnancy loss can be devastating and exert a major impact on women, their partners, and society more broadly, but ...
News Medical14d
Boosting Treg cells shows promise in preventing recurrent pregnancy loss
Recurrent pregnancy loss can be devastating and exert a major impact on women, their partners, and society more broadly, but currently there are few options for effective therapies.
money.rediff14d
I-T Dept Notifies Tolerance Range for Transfer Pricing AY 2024-25
The Income Tax Department has notified the tolerance range for transfer pricing for international and specified domestic transactions for Assessment Year 2024-25. The range remains at 1% for wholesale ...
Phys.org15d
Scientists create a molecular switch that can control cell division on demand outside of a living system
A living cell is a bustling metropolis ... where microtubules overlap and chromosomes are separated. But PRC1 doesn't act alone. Its activity is tightly controlled to ensure that microtubules ...