Glucan-mediated trained immunity activates alveolar macrophages which exacerbates acute lung injury induced by LPS.

Quantitative measurements of intra-Golgi transport kinetics of diverse secretory cargos challenge the classic cisternal progression model and support the stable compartment model of the Golgi.

Platelet-derived growth factors can restore the proliferative potential of senescent cells taken from the degenerated intervertebral discs of aged humans.

The chirality of tissues and organs is essential for their proper function and development. Tissue-level chirality derives from the chirality of individual cells that comprise the tissue, and cellular ...

Here, we address this question further by combining large-scale electrophysiological recordings, to characterize the functional connectivity of developing neuronal networks in vitro, with a generative ...

A compound found in fungal cell walls can reprogram immune cells in the lungs, potentially worsening inflammation during infections.

Reviewer #3 (Public review): Summary: This important study shows that stationary phase bacteria survive antimicrobial peptide treatment by switching on efflux pumps, generating low accumulating ...

eLife Assessment This study makes an important contribution by showing that humans adapt learning rates rationally to environmental volatility yet systematically misattribute noise as volatility, ...

Ascidians (also known as sea squirts) are small marine animals. Ascidian larvae have tadpole-like bodies and swim by beating their tail, but the adults have a vase-like shape, no tail and are attached ...

Exosomal mRNA transfer from non-neuronal cells to neurons under hypoxia drives hemoglobin expression and preserves mitochondrial homeostasis as an intercellular protective mechanism.

Sensorimotor computations for learning and behavior rely on precise patterns of synaptic connectivity. Yet, we typically lack the synaptic wiring diagrams for long-range connections between sensory ...

Proteomics with PP1-Neurabin fusion proteins identify the 4E-BP proteins as novel Neurabin/PP1 substrates, and interaction with the Neurabin PDZ domain shown to be the major determinant of ...