Hemophagocytic lymphohistiocytosis (HLH) is a well-recognised complication of systemic lupus erythematosus (SLE). In one small case series, HLH was noted in approximately 5% of patients with lupus. 1 ...

Case 1: A 28-year-old Mestizo female with diffuse alveolar hemorrhage A 28-year-old Mestizo female was diagnosed with systemic lupus erythematosus (SLE) a year ago, based on fever, polyarthralgia/its, ...

Case 2: An Afro-Caribbean female with atypical chest pain An Afro-Caribbean female presented with neuropsychiatric lupus at the age of 28 years and was treated with intravenous cyclophosphamide. Her ...

Systemic lupus erythematosus (SLE) is associated with increased expression of genes regulated by Type I interferon (IFN) in 50–70% of patients. 1 Previous studies, including our own, have demonstrated ...

A meta-analysis of the four relevant randomized clinical trials evaluating direct oral anticoagulants (DOACs) versus warfarin in thrombotic antiphospholipid syndrome (APS) showed a significant ...

Despite advancements in lupus management over the past two decades, infection remains a significant cause of morbidity and mortality among patients with systemic lupus erythematosus (SLE). 1 2 Various ...

Immune dysregulation in systemic lupus erythematosus (SLE) results in the autoimmune manifestations of SLE, but also leads to an impaired immune response to pathogens and vulnerability to infections ...

As a consequence of increased survival over the last decades, patients with systemic lupus erythematosus (SLE) and their partners have an increased wish for pregnancy. However, pregnancy in SLE is ...

Background The course and evolution of the SLE depends on the affected organ, adherence to treatment and accumulated organ damage, but ethnicity plays a fundamental role, leading to worse results in ...

Objectives To evaluate the time course of clinical response following anifrolumab treatment in patients with SLE. Methods A post hoc analysis was conducted using pooled data from phase III, randomised ...

1 Beijing Hospital of Traditional Chinese Medicine, Capital Medical University, Beijing Institute of Chinese Medicine, Beijing, China Objective Celastrol is a bioactive constituent extracted from ...

Systemic lupus erythematosus (SLE) is a complex autoimmune disorder that frequently involves the kidneys and can ultimately lead to renal replacement therapy or kidney transplantation for severe cases ...