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jax.org
Minute to Understanding: What is epigenetics? - The Jackson Laboratory
Learn how epigenetic changes can affect an individual — without physically changing their DNA sequence.
Sep 14, 2021
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Gene expression, influenced by both DNA and epigenetics, affects emotional regulation and stress responses across generations (Meaney & Szyf, 2005). Trauma-induced epigenetic changes, such as altered DNA methylation, have been observed in descendants of Holocaust survivors (Yehuda et al., 2016) and animals exposed to fear-conditioning (Dias & Ressler, 2014). Variations in 5-HTTLPR (serotonin transport) and COMT (dopamine regulation) genes also contribute to inherited anxiety and mood disorders (
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