Competitive Inhibition & Lineweaver-Burk Plots | Study Prep in Pearson+
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2. The steady state kinetics of the enzyme aspartase were studied in the absence and presence of the inhibitor hydroxymethylaspartate (A) ([A] = 2.5 x 10^-4 M). The initial rate (v) is given as a function of substrate concentration. (8 pts)[S](M)v (no inhibitor)(M/min)v (inhibitor present)(M/min)1 x 10^-40.0260.0105 x 10^-40.0920.0401.5 x 10^-30.1360.0862.5 x 10^-30.1500.1205 x 10^-30.1650.142
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Reversible Inhibition and Lineweaver-Burk Plots - Free Sketchy MCAT Lesson
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1) Draw and briefly explain the log-dose response curve and the corresponding Lineweaver-Burke plot for:a) morphine alone and together with naloxoneb) buprenorphine alone and together with naloxoneThe curves do not have to be based on the actual ED50 values for the compounds. Instead, you have to research howeach of the compounds behave at the µ-opioid receptor (i.e. full or partial agonist, competitive or non-competitiveant agonist, please make sure to cite your references). Based on this infor
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