Does methyl B12 actually trigger your histamine reactions? Most people never question their supplements — but they should. If methyl B12 leaves you anxious, wired, fatigued, or feeling like your old symptoms suddenly came roaring back, you might not be “reacting”… you might be over-methylating. Before you blame histamine, consider this: some bodies simply don’t tolerate the extra methyl groups in methylcobalamin. And if that’s you, no amount of “pushing through” will fix it. The solution? Switch